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Function of pulmonary M2 muscarinic receptors in antigen-challenged guinea pigs is restored by heparin and poly-L-glutamate.

The effect of heparin and poly-L-glutamate on the function of inhibitory M2 muscarinic autoreceptors on parasympathetic nerves in the lung was tested in antigen-challenged guinea pigs. After antigen challenge, M2 receptor function is decreased, thus increasing release of acetylcholine from the vagus...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Fryer, A D, Jacoby, D B
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443381/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1281829/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116116
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