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Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM)

The regulation of mitochondrial biogenesis is under the control of nuclear genes including the master mitochondrial transcription factor A (TFAM). Recent evidence suggests that the expression of TFAM is regulated by microRNAs (miRNAs) in various cellular contexts. Here, we show that hsa-miR-155-5p,...

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Publicado en:Biochim Biophys Acta
Main Authors: Quiñones-Lombraña, Adolfo, Blanco, Javier G.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433801/
https://ncbi.nlm.nih.gov/pubmed/25869329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.04.004
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