C-reactive protein directly suppresses T helper 1 cell differentiation and alleviates experimental autoimmune encephalomyelitis

Human C-reactive protein (CRP) is a serum soluble pattern recognition receptor (PRR) that serves as a marker of inflammation and directly contributes to innate immunity. Herein we show that human CRP also directly contributes to adaptive immunity, i.e. native CRP binds specifically to human Jurkat T...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Zhang, Lin, Liu, Shan-Hui, Wright, Tyler T., Shen, Zhi-Yuan, Li, Hai-Yun, Zhu, Wei, Potempa, Lawrence A., Ji, Shang-Rong, Szalai, Alexander J., Wu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433796/
https://ncbi.nlm.nih.gov/pubmed/25917100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402909
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