Lipolytic catecholamine resistance due to decreased beta 2-adrenoceptor expression in fat cells.
The existence of lipolytic beta-adrenoceptor (BAR) resistance was investigated in vivo and in isolated abdominal subcutaneous adipocytes in 65 healthy and drug-free subjects. The concentration of isoprenaline (nonselective BAR agonist) causing half-maximum lipolysis effect (ED50) varied bimodally an...
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| Vydáno v: | J Clin Invest |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443368/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1334970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116103 |
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