CD40 Ligand Deficient C57BL/6 Mouse Is a Potential Surrogate Model of Human X-Linked Hyper IgM (X-HIGM) Syndrome for Characterizing Immune Responses against Pathogens

Individuals with X-HIGM syndrome fail to express functional CD40 ligand; consequently they cannot mount effective protective antibody responses against pathogenic bacteria. We evaluated, compared, and characterized the humoral immune response of wild type (WT) and C57-CD40L deficient (C57-CD40L(−/−)...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Lopez-Saucedo, Catalina, Bernal-Reynaga, Rodolfo, Zayas-Jahuey, Jesus, Galindo-Gomez, Silvia, Shibayama, Mineko, Garcia-Galvez, Carlos, Estrada-Parra, Sergio, Estrada-Garcia, Teresa
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433659/
https://ncbi.nlm.nih.gov/pubmed/26064940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/679850
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