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Differential Regulation of Connexin 50 and Connexin 46 by PI3K Signaling

Gap junction channels can modify their activity in response to cell signaling pathways. Here, we demonstrate that Cx50 coupling, but not Cx46, increased when co-expressed with a constitutively active p110α subunit of PI3K in Xenopus oocytes. In addition, inhibition of PI3K signaling by blocking p110...

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Publicado en:FEBS Lett
Main Authors: Martinez, Jennifer M., Wang, Hong-Zhan, Lin, Richard Z., Brink, Peter R., White, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433579/
https://ncbi.nlm.nih.gov/pubmed/25935417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.04.029
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