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Four levels of hierarchical organization including non-covalent chainmail brace the mature tumor herpesvirus capsid against pressurization

Like many dsDNA viruses, tumor gammaherpesviruses Epstein-Barr virus and Kaposi’s sarcoma-associated-herpesvirus withstand high internal pressure. Bacteriophage HK97 uses covalent chainmail for this purpose, but how this is achieved non-covalently in the much larger gammaherpesvirus capsid is unknow...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Zhou, Z. Hong, Hui, Wong Hoi, Shah, Sanket, Jih, Jonathan, O’Connor, Christine M., Sherman, Michael B., Kedes, Dean H., Schein, Stan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433476/
https://ncbi.nlm.nih.gov/pubmed/25220471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.05.019
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