N‐terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy

Taxane‐based chemotherapy is an effective treatment for castration‐resistant‐prostate cancer (CRPC) via stabilization of microtubules. Previous studies identified that the inhibitory effect of microtubule‐targeting chemotherapy on androgen receptor (AR) activity was conferred by interfering with AR...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Martin, Sarah K., Banuelos, Carmen A., Sadar, Marianne D., Kyprianou, Natasha
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433435/
https://ncbi.nlm.nih.gov/pubmed/25432105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.10.014
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