N‐terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy

Taxane‐based chemotherapy is an effective treatment for castration‐resistant‐prostate cancer (CRPC) via stabilization of microtubules. Previous studies identified that the inhibitory effect of microtubule‐targeting chemotherapy on androgen receptor (AR) activity was conferred by interfering with AR...

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Vydáno v:Mol Oncol
Hlavní autoři: Martin, Sarah K., Banuelos, Carmen A., Sadar, Marianne D., Kyprianou, Natasha
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2014
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433435/
https://ncbi.nlm.nih.gov/pubmed/25432105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.10.014
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