Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality

Objectives Drug repurposing, which finds new indications for existing drugs, has received great attention recently. The goal of our work is to assess the feasibility of using electronic health records (EHRs) and automated informatics methods to efficiently validate a recent drug repurposing associat...

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Bibliographic Details
Published in:J Am Med Inform Assoc
Main Authors: Xu, Hua, Aldrich, Melinda C, Chen, Qingxia, Liu, Hongfang, Peterson, Neeraja B, Dai, Qi, Levy, Mia, Shah, Anushi, Han, Xue, Ruan, Xiaoyang, Jiang, Min, Li, Ying, Julien, Jamii St, Warner, Jeremy, Friedman, Carol, Roden, Dan M, Denny, Joshua C
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Research and Applications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433365/
https://ncbi.nlm.nih.gov/pubmed/25053577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2014-002649
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