In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury.

The cardioprotective effects of an mAb to P-selectin designated mAb PB1.3 was examined in a feline model of myocardial ischemia (MI) and reperfusion. PB1.3 (1 mg/kg), administered after 80 min of ischemia (i.e., 10 min before reperfusion), significantly attenuated myocardial necrosis compared to a n...

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Библиографические подробности
Главные авторы: Weyrich, A S, Ma, X Y, Lefer, D J, Albertine, K H, Lefer, A M
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC443326/
https://ncbi.nlm.nih.gov/pubmed/7685773
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