The Intestinal Barrier in Irritable Bowel Syndrome: Subtype-Specific Effects of the Systemic Compartment in an In Vitro Model

BACKGROUND: Irritable bowel syndrome (IBS) is a disorder with multifactorial pathophysiology. Intestinal barrier may be altered, especially in diarrhea-predominant IBS (IBS-D). Several mediators may contribute to increased intestinal permeability in IBS. AIM: We aimed to assess effects of tryptase a...

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Udgivet i:PLoS One
Main Authors: Ludidi, Samefko, Jonkers, Daisy, Elamin, Elhaseen, Pieters, Harm-Jan, Schaepkens, Esther, Bours, Paul, Kruimel, Joanna, Conchillo, José, Masclee, Ad
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433176/
https://ncbi.nlm.nih.gov/pubmed/25978614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123498
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