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Hypercholesterolemia increases endothelial superoxide anion production.
Indirect evidence suggests accelerated degradation of endothelium-derived nitric oxide (ENDO) by superoxide anion (O2-) in hypercholesterolemic vessels (HV). To directly measure O2- production by normal vessels (NV) and HV, we used an assay for O2- based on the chemiluminescence (CL) of lucigenin (L...
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| Publicado en: | J Clin Invest |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1993
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8390482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116491 |
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