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Endoplasmic Reticulum Stress Impairs Insulin Receptor Signaling in the Brains of Obese Rats

The incidence of obesity is increasing worldwide. It was reported that endoplasmic reticulum stress (ERS) could inhibit insulin receptor signaling by activating c-Jun N-terminal kinase (JNK) in the liver. However, the relationship between ERS and insulin receptor signaling in the brain during obesit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liang, Lina, Chen, Jing, Zhan, Libin, Lu, Xiaoguang, Sun, Xiaoxin, Sui, Hua, Zheng, Luping, Xiang, Hong, Zhang, Fuliang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433117/
https://ncbi.nlm.nih.gov/pubmed/25978724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126384
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