Interferon-alpha and interleukin 2 synergistically enhance basic fibroblast growth factor synthesis and induce release, promoting endothelial cell growth.

To elucidate mechanisms underlying neovascularization that accompanies certain chronic immune/inflammatory disorders, the effects of interferon-alpha (IFN-alpha) and interleukin 2 (IL-2) on endothelial cell (EC) growth in vitro and angiogenesis in vivo were studied. Preincubation of cultured human E...

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Autors principals: Cozzolino, F, Torcia, M, Lucibello, M, Morbidelli, L, Ziche, M, Platt, J, Fabiani, S, Brett, J, Stern, D
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC443311/
https://ncbi.nlm.nih.gov/pubmed/7685771
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