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Optimal programs of pathway control: dissecting the influence of pathway topology and feedback inhibition on pathway regulation

BACKGROUND: Adjusting the capacity of metabolic pathways in response to rapidly changing environmental conditions is an important component of microbial adaptation strategies to stochastic environments. In this work, we use advanced dynamic optimization techniques combined with theoretical models to...

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發表在:BMC Bioinformatics
Main Authors: de Hijas-Liste, Gundián M, Balsa-Canto, Eva, Ewald, Jan, Bartl, Martin, Li, Pu, Banga, Julio R, Kaleta, Christoph
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433072/
https://ncbi.nlm.nih.gov/pubmed/25982966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0587-z
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