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A multi-SNP association test for complex diseases incorporating an optimal P-value threshold algorithm in nuclear families
BACKGROUND: Genome-wide association studies (GWAS) have become a common approach to identifying single nucleotide polymorphisms (SNPs) associated with complex diseases. As complex diseases are caused by the joint effects of multiple genes, while the effect of individual gene or SNP is modest, a meth...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433014/ https://ncbi.nlm.nih.gov/pubmed/25975968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1620-3 |
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