Guanylin stimulation of Cl- secretion in human intestinal T84 cells via cyclic guanosine monophosphate.

Intestinal salt and fluid secretion is stimulated by Escherichia coli heat-stable enterotoxins (ST) through activation of a membrane guanylate cyclase found in the intestine. Guanylin is an endogenous intestinal peptide that has structural similarity to the bacterial peptides. Synthetic preparations...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Forte, L R, Eber, S L, Turner, J T, Freeman, R H, Fok, K F, Currie, M G
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443301/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8390480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116476
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