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Dimerization of thiol-specific antioxidant and the essential role of cysteine 47.

Thiol-specific antioxidant (TSA) from yeast contains cysteine residues at amino acid positions 47 and 170 but is not associated with obvious redox cofactors. These two cysteines are highly conserved in a family of proteins that exhibit sequence identity of 23-98% with TSA. The roles of Cys-47 and Cy...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Chae, H Z, Uhm, T B, Rhee, S G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041739/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.7022
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