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Cytomegalovirus immediate early genes prevent the inhibitory effect of cyclosporin A on interleukin 2 gene transcription.

The use of cyclosporin A (CsA) as an immunosuppressive agent has markedly improved the clinical outcome in solid organ transplantation. However, posttransplantation infection remains a significant problem and may contribute to subsequent organ rejection. In this study the effect of cytomegalovirus (...

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Vydáno v:J Clin Invest
Hlavní autoři: Geist, L J, Monick, M M, Stinski, M F, Hunninghake, G W
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1331182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116099
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