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Oxygen radical scavengers selectively inhibit interleukin 8 production in human whole blood.

The hydroxyl radical (OH.) scavenger dimethyl sulfoxide (DMSO) was found to dose-dependently inhibit interleukin 8 (IL-8) production in LPS-stimulated human whole blood. At a concentration of 1% (vol/vol), DMSO blocked IL-8 release by approximately 90% in the presence of 1 microgram/ml LPS at a 24-h...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: DeForge, L E, Fantone, J C, Kenney, J S, Remick, D G
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1992
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1331181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116097
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