Therapeutic efficacy and biodistribution of allogeneic mesenchymal stem cells delivered by intrasplenic and intrapancreatic routes in streptozotocin-induced diabetic mice

INTRODUCTION: Mesenchymal stromal/stem cells (MSCs) are multipotent cells that have the ability to express and secrete a wide range of immunomodulatory molecules, cytokines, growth factors and antiapoptotic proteins. MSCs modulate both innate and adaptive immune responses making them potential candi...

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Pubblicato in:Stem Cell Res Ther
Autori principali: Yaochite, Juliana Navarro Ueda, Caliari-Oliveira, Carolina, de Souza, Lucas Eduardo Botelho, Neto, Lourenço Sbragia, Palma, Patrícia Vianna Bonini, Covas, Dimas Tadeu, Malmegrim, Kelen Cristina Ribeiro, Voltarelli, Julio César, Donadi, Eduardo Antônio
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432770/
https://ncbi.nlm.nih.gov/pubmed/25884215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0017-1
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