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Mutations in the ligand-binding domain of the androgen receptor gene cluster in two regions of the gene.

We have analyzed the nucleotide sequence of the androgen receptor from 22 unrelated subjects with substitution mutations of the hormone-binding domain. Eleven had the phenotype of complete testicular feminization, four had incomplete testicular feminization, and seven had Reifenstein syndrome. The u...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: McPhaul, M J, Marcelli, M, Zoppi, S, Wilson, C M, Griffin, J E, Wilson, J D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443277/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1430233/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116093
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