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Role of transforming growth factor-beta in maintenance of function of cultured neonatal cardiac myocytes. Autocrine action and reversal of damaging effects of interleukin-1.

The three isoforms of transforming growth factor-beta (TGF-beta) have previously been implicated in embryonic development of the heart as well as in repair of myocardial damage after ischemia/reperfusion injury. TGF-beta 1 has also been localized intracellularly to both mitochondria and contractile...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Roberts, A B, Roche, N S, Winokur, T S, Burmester, J K, Sporn, M B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443271/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1430228/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116087
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