Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells

CD8(+) T-cell memory phenotype and function are acquired after antigen-driven activation. Memory-like cells may also arise in absence of antigenic exposure in the thymus or in the periphery. Eomesodermin (Eomes) is a key transcription factor for the development of these unconventional memory cells....

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Udgivet i:Nat Commun
Main Authors: Martinet, Valérie, Tonon, Sandrine, Torres, David, Azouz, Abdulkader, Nguyen, Muriel, Kohler, Arnaud, Flamand, Véronique, Mao, Chai-An, Klein, William H., Leo, Oberdan, Goriely, Stanislas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432629/
https://ncbi.nlm.nih.gov/pubmed/25953241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8089
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