Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility

BACKGROUND: Regulated gene expression controls organismal development, and variation in regulatory patterns has been implicated in complex traits. Thus accurate prediction of enhancers is important for further understanding of these processes. Genome-wide measurement of epigenetic features, such as...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Dogan, Nergiz, Wu, Weisheng, Morrissey, Christapher S, Chen, Kuan-Bei, Stonestrom, Aaron, Long, Maria, Keller, Cheryl A, Cheng, Yong, Jain, Deepti, Visel, Axel, Pennacchio, Len A, Weiss, Mitchell J, Blobel, Gerd A, Hardison, Ross C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432502/
https://ncbi.nlm.nih.gov/pubmed/25984238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-015-0009-5
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