Structure-function relationships of interleukin-3. An analysis based on the function and binding characteristics of a series of interspecies chimera of gibbon and murine interleukin-3.

IL-3 is a glycoprotein cytokine involved in the hematopoietic response to infectious, immunologic, and inflammatory stimuli. In addition, clinical administration of recombinant IL-3 augments recovery in states of natural and treatment-related marrow failure. IL-3 acts by binding to high affinity cel...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Kaushansky, K, Shoemaker, S G, Broudy, V C, Lin, N L, Matous, J V, Alderman, E M, Aghajanian, J D, Szklut, P J, VanDyke, R E, Pearce, M K
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1385477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116065
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