In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection

Although small molecules shed from pathogens are widely used to diagnose infection, such tests have not been widely implemented for tuberculosis. Here we show that the recently identified compound, 1-tuberculosinyladenosine (1-TbAd), accumulates to comprise > 1 percent of all M. tuberculosis lipi...

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Detalhes bibliográficos
Publicado no:Chem Biol
Main Authors: Young, David C., Layre, Emilie, Pan, Shih-Jung, Tapley, Asa, Adamson, John, Seshadri, Chetan, Wu, Zhongtao, Buter, Jeffrey, Minnaard, Adriaan J., Coscolla, Mireia, Gagneux, Sebastien, Copin, Richard, Ernst, Joel D., Bishai, William, Snider, Barry B., Moody, D. Branch
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432472/
https://ncbi.nlm.nih.gov/pubmed/25910243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.03.015
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