Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs.

It is generally believed that glucose production (GP) cannot be adequately suppressed in insulin-treated diabetes because the portal-peripheral insulin gradient is absent. To determine whether suppression of GP in diabetes depends on portal insulin levels, we performed 3-h glucose and specific activ...

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Pubblicato in:	J Clin Invest
Autori principali:	Giacca, A, Fisher, S J, Shi, Z Q, Gupta, R, Lickley, H L, Vranic, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443235/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1430203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116051
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