Colitogenic Bacteroides thetaiotaomicron antigens access host immune cells in a sulfatase-dependent manner via outer membrane vesicles

Microbes interact with the host immune system via several potential mechanisms. One essential step for each mechanism is the method by which intestinal microbes or their antigens access specific host immune cells. Using genetically-susceptible mice (dnKO) that develops spontaneous, fulminant colitis...

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Publicado no:Cell Host Microbe
Main Authors: Hickey, Christina A., Kuhn, Kristine A., Donermeyer, David L., Porter, Nathan T., Jin, Chunsheng, Cameron, Elizabeth A., Jung, Haerin, Kaiko, Gerard E., Wegorzewska, Marta, Malvin, Nicole P., Glowacki, Robert W. P., Hansson, Gunnar C., Allen, Paul M., Martens, Eric C., Stappenbeck, Thaddeus S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432250/
https://ncbi.nlm.nih.gov/pubmed/25974305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.04.002
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