Ceftazidime-Avibactam Activity Tested against Enterobacteriaceae Isolates from U.S. Hospitals (2011 to 2013) and Characterization of β-Lactamase-Producing Strains

Ceftazidime-avibactam (MIC(50/90), 0.12/0.25 μg/ml) inhibited 99.9% (20,698/20,709) of Enterobacteriaceae isolates at ≤8 μg/ml. This compound was active against resistant subsets, including ceftazidime-nonsusceptible Enterobacter cloacae (MIC(50/90), 0.25/0.5 μg/ml) and extended-spectrum β-lactamase...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Castanheira, Mariana, Mills, Janet C., Costello, Sarah E., Jones, Ronald N., Sader, Helio S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Epidemiology and Surveillance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432207/
https://ncbi.nlm.nih.gov/pubmed/25845862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00163-15
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