Telaprevir and Ribavirin Interaction: Higher Ribavirin Levels Are Not Only Due to Renal Dysfunction during Triple Therapy

A higher incidence of anemia has been observed during the treatment of hepatitis C virus genotype 1 (HCV-1) infection with pegylated alpha interferon (pegIFN-α), ribavirin, and telaprevir. We assessed the impacts that concomitant administration of telaprevir and changes in the glomerular filtration...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Gutierrez-Valencia, Alicia, Ruiz-Valderas, Rosa, Ben-Marzouk-Hidalgo, Omar J., Torres-Cornejo, Almudena, Espinosa, Nuria, Castillo-Ferrando, Juan R., Viciana, Pompeyo, Lopez-Cortes, Luis F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432178/
https://ncbi.nlm.nih.gov/pubmed/25801562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04795-14
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