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Pharmacokinetics of a Novel Sublingual Spray Formulation of the Antimalarial Drug Artemether in Healthy Adults

The pharmacokinetics of sublingual artemether (ArTiMist) was investigated in two open-label studies. In study 1, 16 healthy males were randomized to each of four single-dose treatments administered in random order: (i) 15.0 mg of sublingual artemether (5 × 3.0 actuations), (ii) 30.0 mg of sublingual...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Salman, Sam, Bendel, Daryl, Lee, Toong C., Templeton, David, Davis, Timothy M. E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432176/
https://ncbi.nlm.nih.gov/pubmed/25801553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05013-14
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