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Artemisinin-Resistant Plasmodium falciparum Parasites Exhibit Altered Patterns of Development in Infected Erythrocytes

Artemisinin derivatives are used in combination with other antimalarial drugs for treatment of multidrug-resistant malaria worldwide. Clinical resistance to artemisinin recently emerged in southeast Asia, yet in vitro phenotypes for discerning mechanism(s) of resistance remain elusive. Here, we desc...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Hott, Amanda, Casandra, Debora, Sparks, Kansas N., Morton, Lindsay C., Castanares, Geocel-Grace, Rutter, Amanda, Kyle, Dennis E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432152/
https://ncbi.nlm.nih.gov/pubmed/25779582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00197-15
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