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Influence of ABCC2 and ABCC4 Polymorphisms on Tenofovir Plasma Concentrations in Thai HIV-Infected Patients

Tenofovir (TFV) is eliminated by renal excretion, which is mediated through multidrug-resistant protein 2 (MRP2) and MRP4, encoded by ABCC2 and ABCC4, respectively. Genetic polymorphisms of these transporters may affect the plasma concentrations of tenofovir. Therefore, the aim of this study was to...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antimicrob Agents Chemother
मुख्य लेखकों: Rungtivasuwan, Kanokrat, Avihingsanon, Anchalee, Thammajaruk, Narukjaporn, Mitruk, Siwaporn, Burger, David M., Ruxrungtham, Kiat, Punyawudho, Baralee, Pengsuparp, Thitima
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432150/
https://ncbi.nlm.nih.gov/pubmed/25801567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04930-14
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