Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem during the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units

Pathophysiological changes during the early phase of severe sepsis and septic shock in critically ill patients, resulting in altered pharmacokinetic (PK) patterns for antibiotics, are important factors influencing therapeutic success. The aims of this study were (i) to reveal the population PK param...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jaruratanasirikul, Sutep, Thengyai, Suriyan, Wongpoowarak, Wibul, Wattanavijitkul, Thitima, Tangkitwanitjaroen, Kanyawisa, Sukarnjanaset, Waroonrat, Jullangkoon, Monchana, Samaeng, Maseetoh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432146/
https://ncbi.nlm.nih.gov/pubmed/25753628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04166-14
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