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Cytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production. Evidence for cytokine-regulated hyaluronan (hyaluronic acid) degradation and human lung fibroblast-derived hyaluronidase.

We characterized the mechanisms by which recombinant (r) tumor necrosis factor (TNF), IFN-gamma, and IL-1, alone and in combination, regulate human lung fibroblast hyaluronic acid (HA) production. Each cytokine stimulated fibroblast HA production. The combination of rTNF and rIFN-gamma resulted in a...

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Sampson, P M, Rochester, C L, Freundlich, B, Elias, J A
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116017
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