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Evidence for defective transmembrane signaling in B cells from patients with Wiskott-Aldrich syndrome.
B lymphocytes from patients expressing the X chromosome-linked immune deficiency disorder, Wiskott-Aldrich syndrome (WAS), fail to produce antibodies in response to stimulation with polysaccharides and other type-2 T cell-independent antigens. To investigate whether this abnormality reflects a defec...
Uloženo v:
| Vydáno v: | J Clin Invest |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401074/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116006 |
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