Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

It is well accepted that aging and HIV infection are associated with quantitative and functional changes of CMV-specific T cell responses. We studied here the expression of Mip-1β and the T cell maturation marker CD27 within CMVpp65-specific CD4(+) and CD8(+) T cells in relation to age, HIV and acti...

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Veröffentlicht in:PLoS One
Hauptverfasser: Portevin, Damien, Moukambi, Félicien, Mpina, Maxmillian, Bauer, Asli, Haraka, Frederick, Chachage, Mkunde, Metzger, Philipp, Saathoff, Elmar, Clowes, Petra, Ntinginya, Nyanda E., Rachow, Andrea, Hoelscher, Michael, Reither, Klaus, Daubenberger, Claudia A., Geldmacher, Christof
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431818/
https://ncbi.nlm.nih.gov/pubmed/25974183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126716
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