Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha.

The epidermal growth factor (EGF) receptor is activated by both EGF and transforming growth factor-alpha (TGF-alpha). Using immunohistochemical and immunoblotting techniques we now report that the EGF receptor, EGF, and TGF-alpha are found in both pancreatic acini and ducts in the normal human pancr...

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Pubblicato in:	J Clin Invest
Autori principali:	Korc, M, Chandrasekar, B, Yamanaka, Y, Friess, H, Buchier, M, Beger, H G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443180/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401070/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116001
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