Aurora B Kinase Promotes Cytokinesis by Inducing Centralspindlin Oligomers that Associate with the Plasma Membrane

In metazoans, cytokinesis is triggered by activation of the GTPase RhoA at the equatorial plasma membrane. ECT-2, the guanine nucleotide exchange factor (GEF) required for RhoA activation, is activated by the centralspindlin complex that concentrates on spindle midzone microtubules. However, these m...

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Bibliografske podrobnosti
izdano v:Dev Cell
Main Authors: Basant, Angika, Lekomtsev, Sergey, Tse, Yu Chung, Zhang, Donglei, Longhini, Katrina M., Petronczki, Mark, Glotzer, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431772/
https://ncbi.nlm.nih.gov/pubmed/25898168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.03.015
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