Inhibition of apical Na+ channels in rabbit cortical collecting tubules by basolateral prostaglandin E2 is modulated by protein kinase C.

We used the cell-attached patch clamp technique to investigate the interaction of exogenous prostaglandins (PG), intracellular [Ca2+]i, and protein kinase C (PKC) on the high selectivity, 4 pS Na+ channel found in the principal cell apical membrane of rabbit cortical collecting tubule (CCT) cultures...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Ling, B N, Kokko, K E, Eaton, D C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115998
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