PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis

AIMS: Vascular injury leading to endothelial dysfunction is a characteristic feature of chronic renal disease, diabetes mellitus, and systemic inflammatory conditions, and predisposes to apoptosis and atherogenesis. Thus, endothelial dysfunction represents a potential therapeutic target for atherosc...

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Bibliographic Details
Published in:Cardiovasc Res
Main Authors: Mylroie, Hayley, Dumont, Odile, Bauer, Andrea, Thornton, Clare C., Mackey, John, Calay, Damien, Hamdulay, Shahir S., Choo, Joan R., Boyle, Joseph J., Samarel, Allen M., Randi, Anna M., Evans, Paul C., Mason, Justin C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431664/
https://ncbi.nlm.nih.gov/pubmed/25883219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv131
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