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Reduction-responsive cross-linked stearyl peptide for effective delivery of plasmid DNA
Low efficiency and significant toxicity are the main obstacles to successful gene delivery. We have developed a cationic reduction-responsive vector based on a disulfide cross-linked stearylated polyarginine peptide modified with histidine (C-SHR) for DNA delivery. The structure of the C-SHR was cha...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Int J Nanomedicine |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Dove Medical Press
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4431505/ https://ncbi.nlm.nih.gov/pubmed/26056440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S82413 |
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