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Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice.

The opportunistic pathogen Pneumocystis carinii (Pc) is considered to be the leading cause of morbidity in patients with AIDS. It is important, therefore, to determine the immunological mechanisms of resistance to Pc. We have taken advantage of the lack of both T and B lymphocytes in severe combined...

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Détails bibliographiques
Auteurs principaux: Roths, J B, Sidman, C L
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC443150/
https://ncbi.nlm.nih.gov/pubmed/1353767
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