Proton pump inhibitors (PPIs) impact on tumour cell survival, metastatic potential and chemotherapy resistance, and affect expression of resistance-relevant miRNAs in esophageal cancer

BACKGROUND: Neoadjuvant treatment plays a crucial role in the therapy of advanced esophageal cancer. However, response to radiochemotherapy varies widely. Proton pump inhibitors (PPIs) have been demonstrated to impact on chemotherapy in a variety of other cancers. We analyzed the impact of PPI treat...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Lindner, Kirsten, Borchardt, Christiane, Schöpp, Maren, Bürgers, Anja, Stock, Christian, Hussey, Damian J, Haier, Jörg, Hummel, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431491/
https://ncbi.nlm.nih.gov/pubmed/25175076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0073-x
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