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Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier

A weakening of the gut mucous barrier permits an increase in the access of intestinal luminal contents to the epithelial cells, which will trigger the inflammatory response. In inflammatory bowel diseases, there is an inappropriate and ongoing activation of the immune system, possibly because the in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gouyer, Valérie, Dubuquoy, Laurent, Robbe-Masselot, Catherine, Neut, Christel, Singer, Elisabeth, Plet, Ségolène, Geboes, Karel, Desreumaux, Pierre, Gottrand, Frédéric, Desseyn, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431476/
https://ncbi.nlm.nih.gov/pubmed/25974250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09577
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