Evidence for reactive nitrogen intermediates in killing of staphylococci by human neutrophil cytoplasts. A new microbicidal pathway for polymorphonuclear leukocytes.

In anucleate, granule-poor, motile fragments from human blood neutrophils (cytokineplasts; CKP), the nitric oxide synthase inhibitor N omega-monomethyl-L-arginine (NMMA) produced a modest decrease in uptake of staphylococci from supernatants (P less than 0.02, n = 7), and a marked decrease in the ki...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Malawista, S E, Montgomery, R R, van Blaricom, G
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1379614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115903
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