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Peptides related to the carboxyl terminus of human platelet factor IV with antibacterial activity.

A peptide (C13) corresponding to the last 13 amino acids of the carboxyl terminus of human platelet factor IV was found to be antibacterial. Amino acid substitutions predicted to disrupt either the amphipathic or alpha-helical nature of C13 rendered the peptide inactive. Antibacterial activity was d...

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Bibliografiske detaljer
Main Authors: Darveau, R P, Blake, J, Seachord, C L, Cosand, W L, Cunningham, M D, Cassiano-Clough, L, Maloney, G
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC443120/
https://ncbi.nlm.nih.gov/pubmed/1644916
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