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Rationally Designing Aptamer Sequences with Reduced Affinity for Controlled Sensor Performance

The relative ease of predicting the secondary structure of nucleic acid sequences lends itself to the design of sequences to perform desired functions. Here, we combine the utility of nucleic acid aptamers with predictable control over the secondary structure to rationally design sequences with cont...

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Detalhes bibliográficos
Publicado no:Sensors (Basel)
Main Authors: Schoukroun-Barnes, Lauren R., White, Ryan J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431182/
https://ncbi.nlm.nih.gov/pubmed/25835184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s150407754
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