Left ventricular systolic and diastolic dysfunction after infusion of tumor necrosis factor-alpha in conscious dogs.

We used a load-insensitive index of systolic left ventricular (LV) function and an analysis of diastolic pressure-dimension relationships to test the hypothesis that recombinant human (rh) tumor necrosis factor-alpha (TNF alpha) impairs LV function in dogs. Animals were studied 7-10 d after aseptic...

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Pubblicato in:	J Clin Invest
Autori principali:	Pagani, F D, Baker, L S, Hsi, C, Knox, M, Fink, M P, Visner, M S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1644912/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115873
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